CLICK CHEMISTRY

GenieTAG

CLICK CHEMISTRY MADE SIMPLE

RAPID AZIDE INSTALLATION

CREATE NEW BIOLOGICS

HOW IT WORKS

GenieTAGTM, the company’s first commercially available, patent pending product is a small molecular weight site-specific (~200 Da), highly  hydrophilic “linker”. It allows  introduction of a single azide functional group to the protein of interest in a simple, quick and non-enzymatic way. This all comes with the added benefit of allowing the end-user to (optionally) remove the installed linker via a controlled reversible reaction, leaving the native protein untouched. 

After GenieTAGTM has been installed on a protein of interest, the azide-functional group opens the door to a plethora of different payloads that can be conjugated via Click Chemistry – a technique that was recently awarded the Nobel Prize in 2022. 

 

WATCH our video for more detail~

KEY BENEFITS

  • Small chemical linker
  • Exclusively labels N-termini of proteins
  • Compatible with most common N-terminal sequences
  • Very mild reaction conditions (pH 7)
  • Rapid (1-3h)
  • Achieves near complete conversion with negligible off-site labelling

TRY IT TODAY

GenieTAG

Synonyms:
6-azido-6-deoxy-D-glucono-1,5-lactone 

Empirical Formula:
C6H9N3O5
CAS Number:              Molecular Weight:
       –                                    203.15