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Click Chemistry

Use our toolbox to
build bioconjugates
with ease

Non-specific Click Chemistry 

Site-specific Chemsitry 

Payloads

Non-specific Chemistry

Most non-specific chemistries involve reactions between primary amines and NHS esters or sulfhydryls and maleimides. We apply these non-specific reactions  to scaffolds, Virus-like-particles (VLPs), lipid nanoparticles (LNPs) and exosomes, decorating their surface for subsequent attachment of a desired payload.

Speak with one of our bioconjugation scientists and together let’s find the best solution for your application.

GenieTAG

GenieTAGTM is a small molecular weight site-specific (~200 Da), highly  hydrophilic linker. It allows  introduction of a single azide functional group to the protein of interest in a simple, quick and non-enzymatic way

After GenieTAGTM has been installed on a protein of interest, the azide-functional group opens the door to a plethora of different payloads that can be conjugated via Click Chemistry

Synonyms:

6-azido-6-deoxy-D-glucono-1,5-lactone 

Empirical Formula:
C6H9N3O5
CAS Number:              Molecular Weight:
       –                                    203.15
 

Site-specificity made simple

  • Small chemical linker
  • Exclusively labels N-termini of proteins
  • Very mild reaction conditions (pH 7)
  • Rapid (1-3h)

Payloads

From fluorophores to immunomodulatory molecules, find the right payload for your application

Leverage our linker design and expertise to find the right solution for your application. 

What we can conjugate:

  • Peptides
  • Oligonucleotides
  • TLR agonists
  • Cytotoxic drugs
  • Oligosaccharides
  • Fluorophores
  • Reporter enzymes

Private Policy

© 2024

Site-specific chemistries,
payloads & ready-made
conjugates

Explore our bioconjugation toolbox and Purchase off-the-shelf products developed for your early stage research.