Monomeric antigens can be poorly immunogenic, and its multimerisation can confer single shot seroconversion and better Ab responses, due to improved drainage to lypmh nodes and certain VLPs packaging TLR adjuvants.
Furthermore oriented antigen display can produce better quantitative and qualitative Abs than random display.
Why use Site-Specific Conjugation to Multimerize?
Use our technology to orient the display of any antigen or agonist of choice onto a nanoparticle for improved outcome. Our technology is simple, fast and robust, accelerating the research and development pipeline of your Prophylactic or Therapeutic Vaccine strategies.